US Secretary of State Marco Rubio and Special Envoy Steve Witkoff are set to address Congress virtually regarding a developing US-Iran agreement, signaling a significant diplomatic moment in relations with one of Israel's most declared enemies. Iran's nuclear ambitions and its repeated vows to destroy Israel place any US-Iran deal at the centre of prophetic concern, as Scripture warns of a coming coalition of nations aligned against Israel in the last days. The prophet Ezekiel identifies Persia — modern-day Iran — as a key participant in the end-times assault on Israel described in Ezekiel 38–39.